Serological diagnosis of PRRS
A definitive diagnostic evaluation of PRRS with respect to clinical disease requires that serological information be interpreted in combination with results from other virus assays.
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Dr. Kyoungjin Yoon is a Professor in the College of Veterinary Medicine at Iowa State University and is a ACVM board certified veterinary virologist. Prof. Yoon received his veterinary training (DVM, 1985) and master degree (1987) in Preventive Veterinary Medicine from Seoul National University in Korea and earned PhD (1995) in Veterinary Microbiology at Iowa State Unviersity. Since 1995, he has been on the faculty at the veterinary college of Iowa State University and has also been serving the Veterinary Diagnostic Laboratory as Section Leader of Virology and Molecular Microbiology. Prof. Yoon is also academically affiliated with the University of Nebraska in Lincoln, Nebraska (Adjunct Professor) and Qingdao Agricultural University in China (Guest Professor). Besides academic affiliations, he has served on editorial board for numerous journals and is currently Virology Scientific Editor for the Journal of Veterinary Diagnostic Investigation and an Academic Editor for PLoS One.
Prof. Yoon’s research interests focus on viral infections of livestock, particularly swine and bovine, related to the pathogenesis, diagnostics, and prevention and control including disease ecology. As he is affiliated with the ISU Veterinary Diagnostic Laboratory, research in his laboratory frequently uses case materials and questions raised by veterinarians and producers. Currently Prof. Yoon’s laboratory has numerous active research projects on porcine reproductive and respiratory syndrome (PRRS) virus, influenza viruses, porcine rotaviruses, porcine epidemic diarrhea (PED) virus, and paramyxoviruses. All of these research projects have a good combination of in-vitro, ex-vivo and in-vivo studies. To date, Prof. Yoon has published more than 130 refereed publications and has authored 18 book chapters including editing 3 books or monographs. He has authored or co-authors more than 400 conference proceedings and abstracts for national and international conferences, congresses and symposia. He has made more than 180 invited speaker presentations. A most recent example of invited presentations is keynote speech on PED at 2014 IPVS Congress in Cancun, Mexico.
Updated CV 13-Jan-2015
A definitive diagnostic evaluation of PRRS with respect to clinical disease requires that serological information be interpreted in combination with results from other virus assays.
PCR is expensive relative to other diagnostic methods.It should be kept in mind that a positive result on PCR indicates the presence of viral RNA and does not necessarily indicate the presence of infectious PRRSV.
Any tentative clinical diagnosis then should be confirmed by detection of PRRSV (infectious virus, viral antigens and/or viral genomic material) in affected pigs using laboratory methods in conjunction with typical lesions.
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