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The third Merial Forum ‘Update on Pig Production and PCVD’, held in Malta, was the occasion of the formal launch of the piglet indication of CIRCOVAC® in the EU. Over 200 delegates from Europe and beyond attended lectures presenting clinical results from Europe, Asia and South America after piglet, sow, or piglet-plus-sow vaccination with CIRCOVAC, Merial's PCV2 vaccine.The piglet indication registration step was taken by Merial “because the need was clearly expressed by different markets and by practitioners in the field”, Sophie Randoux, Technical and Marketing Director for Production Animals, underlined. “This claim makes CIRCOVAC the first PCV2 vaccine worldwide with both sow and piglet indications”.
Dr Sergio Lopez Soria (CReSA, Barcelona) presented an update on PCVD (porcine circovirus diseases) in 2011, confirming that sub-clinical infection by PCV2 was measurable when piglets from the field were transferred to experimental facilities. Dr Laurent Fischer (R&D, Merial Lyon) presented trial results from the CIRCOVAC registration file, demonstrating that not only PCV2 viraemia and mean viral load were significantly decreased in piglets vaccinated with CIRCOVAC, but also that they had a lower level and duration of faecal excretion.
‘Significant improvements’ in the field
Field experience with piglet CIRCOVAC vaccination was provided by experts from different continents. Dr Maria Nazare Torres Simoes (swine practitioner, Brazil) reported the results of duplicate trials on large farms with a documented history of PCVD, where vaccinated piglets not only had improved performances, but also presented less lung lesions and more disease-free lungs at slaughter.
Dr Henry Too (Technical Director, Merial Asia) presented several piglet vaccination trials, including a blinded, randomised and controlled trial conducted on a Japanese farm. All performance parameters were significantly better among vaccinates, and who also had a lower viraemia (measured by PCR) at 18 weeks of age.
From Europe, Dr Luis Alberto Garcia Pino (Inga Food, Spain) explained how PCV2 piglet vaccination had become a systematic preventive measure in Spain’s second integrator (1 million pigs slaughtered per year). Being sceptical about the impact of PCV2 on performances, a first pilot study was performed, which was promising. By mid-2009, all weaners were vaccinated with CIRCOVAC, with a return on investment varying from 4.2 to 5.8 according to the regions.
Prof. Mathias Ritzmann (University of Veterinary Medicine, Vienna, Austria) presented the results of a controlled randomised field trial that took place on a 250-sow farrow-to-finish farm. CIRCOVAC-vaccinated piglets had a highly significantly improved average daily weight gain and decreased mortality over the entire fattening period (p<0.001), as compared to placebo-injected piglets. Other trials on piglet vaccination from the UK, Italy and France were presented by practitioners, with comparable significant improvements.
Sow-plus-piglet vaccination
The last third of the Forum highlighted the prevention of reproductive disorders in sows, where up-to-date experimental results were presented by Prof. Hans Nauwynck (University of Ghent, Belgium), Prof. Giuseppe Sarli (University of Bologna, Italy). All these data confirm that PCV2 infection both by the intra-uterine and transplacental routes is possible, and that foetal damage can be restricted to a limited fraction of a litter.
Dr Milena Grozeva (SAM BS Ltd, Bulgaria) reported how mass piglet vaccination protocol was implemented on a 2,700-sow Bulgarian farm from the DanBred network, followed by the usual piglet vaccination at weaning. Six months after the implementation of this protocol, mass vaccination of the breeding animals was undertaken, and sow plus piglet CIRCOVAC vaccination became a routine from December 2009 onwards. Results show a progressive improvement of growth performance, levelling out at 1060 g/d during the fattening period once both sows and piglets were vaccinated. Also, the number of weaned piglets per litter had improved by 0.8 over 15 months (p<0.05), reflected by the 13.2 kg increased weaned litter weight (at 97.2 kg) since vaccinating both sows and piglets.
CIRCOVAC®, the only proven “Whole HERD PCV2” vaccine, for use in controlling PCV2 infections through sow or piglet application.
Merial
