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HIPRA España

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359 Followers 7 Publications

HIPRA es una empresa farmacéutica biotecnológica enfocada en la prevención para la salud animal y humana, con una amplia gama de vacunas altamente innovadoras y un servicio de diagnóstico avanzado.

HIPRA trabaja con los últimos avances tecnológicos para crear soluciones que mejoren la salud global.

Los proyectos de I+D constituyen el núcleo del conocimiento, y es que, HIPRA cuenta con más de 50 años de experiencia dedicados a la investigación y desarrollo de diferentes vacunas. Con un modelo organizativo único, controla internamente todos los procesos de la cadena de valor, generando un know-how singular y convirtiéndose en un referente en la investigación, producción y comercialización de biológicos.

HIPRA tiene una sólida presencia internacional, las filiales comerciales y una red de distribución global, permiten que los productos lleguen a clientes de más de 100 países, cubriendo así los 5 continentes.

Actinobacillosis/porcine pleuropneumonia Aujeszky's disease Autogenous vaccines Circovirus/PCV Clostridiosis Colibacillosis Glaesserella parasuis/Glässer's disease Influenza/flu Erysipelas Mycoplasma/Enzootic pneumonia Parvovirus PRRS Atrophic rhinitis

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https://www.hipra.com

hipra@hipra.com

+34 972430660

Av. La Selva, 135
17170 GIRONA
Spain

HIPRA España

359 Followers 7 Publications

Activity Products 20 Events 2 Publications 7 Sponsored articles on 333 80

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PRRSV in Europe: where did it come from?

The great genetic diversity of East European strains has practical implications, the sensitivity of some of the diagnostic PCR methods can be compromised and the efficacy of the current PRRSV vaccines against the East European genetic variants still needs to be elucidated.

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Serological diagnosis of PRRS

A definitive diagnostic evaluation of PRRS with respect to clinical disease requires that serological information be interpreted in combination with results from other virus assays.

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Laboratory detection of PRRS virus

PCR is expensive relative to other diagnostic methods.It should be kept in mind that a positive result on PCR indicates the presence of viral RNA and does not necessarily indicate the presence of infectious PRRSV.

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Diagnosis of PRRS

Any tentative clinical diagnosis then should be confirmed by detection of PRRSV (infectious virus, viral antigens and/or viral genomic material) in affected pigs using laboratory methods in conjunction with typical lesions.

PRRSv infection in France: clinical and economic impact

The cost of PRRS ranges from €17 to €185/sow/year in the three studies presented.

PRRS eradication in Chile: successful experience and disease re-break

From 2000 to 2007 a PRRSv eradication plan was developed successfully in Chile. in October 2013 the spread of a new PRRS virus to several important Chilean pig companies was confirmed.

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Highly Pathogenic PRRS (HP-PRRS) in Asia

A lot of work needs to be done for controlling HP-PRRS completely. The implementation of proper regional control and eradication programs against PRRS is necessary in China and the Asian countries. Meanwhile, the increasing diversity of the PRRSV should be taken into consideration for developing more effective and safe vaccines.

Use and interpretation of sequencing in PRRSV control programs

A comprehensive picture of viral variation at the beginning of control and elimination projects is critical for effective monitoring of progress and effectiveness of implementation procedures, and for identification of new virus introductions to farms and to the region.

Prevention of transplacental PRRSV infection

There are still unknown factors that prevent or block PRRSV replication in the endometrium and the not sufficient number of susceptible cells in the placenta might join forces and cause resistance to placental/transplacental PRRSV infection before 90 days of gestation.

PRRSV transmission via boar semen

Monitoring protocols in boar studs are often insufficient to timely detect an infection.

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PRRS regional control in Europe: the Dutch project is one year on the road!

The first goal of the project is to control PRRSv-infections in order to produce negative offspring.

Transmission, biosecurity, and area regional control/elimination of PRRSV

A risk of airborne transmission of PRRSV is real, and air filtration can significantly reduce its risk. Area regional approach on PRRSV control/elimination indicates our direction where we should move forward in future.

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PRRSv stability in manure and implications for transport biosecurity

About 50% of the vehicles used for transporting pigs in the United States are not washed between loads, so this article evaluates the ability of heating treatments to inactivate PRRSv present in manure-contaminated environments.

The role of host genetics in the response of pigs to PRRSV infection

Clinical disease and outcome following PRRS infection has significant inherited components.

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Dealing with PRRSv-positive breeding herds

Is the right strategy to get a farm stable, that is, control clinical signs reducing the economic impact of the disease; or should a farm adopt strategies to go “negative”? As for other questions in the epidemiological field, our answer is “it depends”.

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PRRS virus elimination: How to prove herd negativity?

One of the challenges when conducting a disease elimination project is to ensure that the pathogen has in deed been eliminated from the herd.

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Vaccination against PRRSV: a practical approach

In general terms, immunization through vaccination is the easiest and safest way to stabilize a herd.

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PRRSV: Interaction with other respiratory pathogens

PRRSV by itself may induce mild-to-severe respiratory disease but rarely results in mortality.

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PRRS Immunology

Resolving the basis of viral and host variation will require identification and characterization of key B- and T-cell epitopes conserved among diverse PRRSV, and of the molecular and structural details of key effector antibodies, T-cell antigen receptors, and MHC molecules that mediate broad, cross-protective immunity.

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The cost of PRRS to pork producers

The total cost of productivity losses to US producers is estimated at US$664 million annually but productivity losses are shifting from the growing pig herd to the sow herd.

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