Abstracts - Pig health

Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function

This work could inform contingency planning that would lead to cost savings in the event of a future FMD outbreak and could also be applied to other infectious diseases.

African swine fever (ASF) is a major pig health problem, and the causative virus is moving closer to Western European regions where pig density is high. Stopping or slowing down the spread of ASF requires mitigation strategies that are both effective and practical.

Feed additives that contained phosphoric acid, citric acid, or fumaric acid were the most effective in reducing virus survival.

We detected a recently discovered pestivirus, termed atypical porcine pestivirus (APPV) in all these cases by RT-PCR.

These studies are the evidences that indirect transmission of PEDV through contaminated personnel, which occurs rapidly, and how fomite material and temperature impact viral stability over time.

We demonstrate the asymptomatic circulation of IAV-S in the Vietnamese pig population.

This study was aimed at evaluating the clinical protection, the level of Porcine circovirus type 2 (PCV2) viremia and the immune response (antibodies and IFN-γ secreting cells (SC)) in piglets derived from PCV2 vaccinated sows and themselves vaccinated against PCV2 at different age, namely at 4, 6 and 8 weeks.

The aim of the study was to determine both environmental and infectious factors, influencing occurrence of bacterial enteropathogens in suckling piglets.

The antibody response and pattern of shedding of vaccine virus following vaccination with modified live genotype I or II porcine reproductive and respiratory syndrome virus (PRRSV) vaccines (MLVs) were investigated.

The data present bronchial scraping as an equally effective or even better alternative to bronchoalveolar lavage fluid for detecting main porcine respiratory disease complex agents.

Immune response-related interactions between T. suis and O. dentatum were detected in co-infected pigs. These interactions reflect an antagonistic effect exerted by T. suis on O. dentatum populations.

The results of this study suggest that metagenomic sequencing is a powerful tool for virus detection and characterization.

Very few studies about the impact of microbial cleaning and administration during production on the environment in animal houses is available. Our results showed that competitive exclusion by probiotic type bacteria is not a valuable alternative for classical C&D.

Of 30 environmental samples collected from a nursery room on our initial visit, 2 (7%) samples yielded 3 isolates: 2 ST 218 Escherichia coli and 1 Proteus mirabilis, carrying the metallo-β-lactamase gene blaIMP-27 on IncQ1 plasmids.

In general, all oxytetracycline doses used for the treatment of Lawsonia intracellularis infection resulted in reduced diarrhoea and Lawsonia intracellularis shedding after treatment.

The differences in shedding pattern and cytokine and immune responses are important for studies of disease pathogenesis and assessment of vaccine protective efficacy.

Findings suggest that concentrated swine feeding operations amplified transmission of influenza during years in which H1N1 was circulating.

In the year following the outbreak, the same PRRSV strain was identified repeatedly in different regions of Austria. It can be speculated that the new strain has novel advantageous properties.

This study used oxytetracycline (OTC) as a model antibiotic to study antibiotic degradation behavior in manure under the above two OTC addition methods.

Our data shows that natural infection by contact induces remarkably high innate and adaptive immune response, although the animals were exposed to a very low virus dose.

Mycoplasma hyopneumoniae pre-infection affected neither the influenza virus replication nor the IFN-induced antiviral responses in lungs. However, it predisposed the animals to a higher inflammatory response to H1N1 infection.

NADC30-like PRRSV has widely spread in China and could cause clinical disease on pigs.

This study identified preventable routes of MRSA CC398 introduction and transmission: human occupational exposure, trade of pigs and livestock transport vehicles.