Webinar: Swine production systems in Africa
X
XLinkedinWhatsAppTelegramTelegram
0

Belgium - Project to eliminate MRSA in pigs

The aim of this project is to eliminate MRSA in pigs, or at least achieve a significant reduction in the level of colonisation, thus lowering or preventing the risk of human beings being infected. To achieve this, phage endolysins are over-produced in E. coli or Pichia pastoris. They are purified for use in the in vivo treatment of experimentally infected animals.
7 April 2010
X
XLinkedinWhatsAppTelegramTelegram
0
The aim of this project is to eliminate MRSA in pigs, or at least achieve a significant reduction in the level of colonisation, thus lowering or preventing the risk of human beings being infected. To achieve this, phage endolysins are over-produced in E. coli or Pichia pastoris. They are purified for use in the in vivo treatment of experimentally infected animals.

The specific objectives of the project are:
• To isolate and over-produce a representative collection of phage-coded lysins acting against specific MRSA clones from pigs;
• To characterise the host range of these enzymes;
• To study the efficiency, in vitro and in animal models, of the bactericide action of these phage enzymes;
• To test methods for administering the phage enzyme preparation in the nose and on the skin of pigs;
• To test the efficiency of the phage enzyme treatment in eliminating MRSA colonisation in pigs.

http://www.var.fgov.be/index.php?option=com_content&view=article&id=314%3Anouveau-traitement-contre-les-mrsa-chez-les-porcs-nouveau-projet-qmrsa-fagen-iwtq&catid=181%3Alatest-news&Itemid=264&lang=fr

Article Comments

This area is not intended to be a place to consult authors about their articles, but rather a place for open discussion among pig333.com users.
Leave a new Comment

Access restricted to 333 users. In order to post a comment you must be logged in.

You are not subscribed to this list pig333.com in 3 minutes

Weekly newsletter with all the pig333.com updates

Log in and sign up on the list

Related articles

MRSA thrives even without antibiotics

17-Oct-2011
The MRSA bacterium, which is resistant to antibiotics, has spread rapidly in the past few years on pig farms. Extensive use of antibiotics is thought to help it spread, but reducing the use of antibiotics is not enough to eliminate MRSA on pig farms.

Welcome to 333

Connect, share, and interact with the largest community of professionals in the swine industry.

Celebrating 153424Users on 333!

Sign upAlready a member?

The most...

tags

Sign uplogin