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ISU researchers discover mystery virus that causes tremors in piglets

A team of veterinary researchers at Iowa State University has pinpointed a virus that has caused mysterious tremors in piglets dating back decades.

6 November 2015
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A team of veterinary researchers at Iowa State University has pinpointed a virus that has caused mysterious tremors in piglets dating back decades.

The virus, which comes from a family known as ‘pestiviruses,’ infects young pigs and can cause them to shake involuntarily. Afflicted piglets are sometimes referred to as “shaker pigs” or “dancing pigs,” and, in severe cases, the tremors prevent pigs from nursing and can lead to starvation.

Veterinarians have recognized the congenital tremors for years but could never pinpoint the cause until now, said Bailey Arruda, an assistant professor and veterinary pathologist in the ISU Department of Veterinary Diagnostic and Production Animal Medicine.

“It’s been a mystery in the veterinary community for over 90 years,” Arruda said. “Unfortunately, we didn’t have the technology to find the virus before.”

The team of researchers utilized next-generation DNA sequencing techniques to detect the virus in samples from affected pigs. The team then used those results to experimentally reproduce the tremors in newborn pigs.

The ISU Veterinary Diagnostic Laboratory can now use PCR tests to confirm cases from samples sent in from local veterinarians. And the next step is to develop a vaccine to combat the virus, she said.

Tuesday November 3, 2015/ Iowa State University/ United States.
http://www.news.iastate.edu

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