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United States: third strain of Porcine Epidemic Diarrhea Virus

Three naturally occurring US PEDV strains have been identified: the original PEDV, the PEDV with changes in the spike gene (INDEL), and the PEDV strain (S2aa-del).

8 January 2015
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A new strain of Porcine Epidemic Diarrhea virus (PEDv) has been recently confirmed by the University of Minnesota Veterinary Diagnostic Laboratory.

Thus far, 3 naturally occurring US PEDV strains have been identified: the original PEDV, the PEDV with changes in the spike gene (INDEL), and the PEDV strain (S2aa-del).

The role of genetic changes in the US PEDV strains to clinical disease has yet to be reported. The clinical presentation of diarrhea in this case was reported as equally or more severe than such presentation in cases caused by the prototype PEDV Colorado/2013. Other factors such as concurrent infections and the rate of group exposure, which is rapid in most PEDV cases affecting neonatal piglets, may influence the clinical presentation.

Marthaler D, Bruner L, Collins J, Rossow K. Third strain of porcine epidemic diarrhea virus, United States [letter]. Emerg Infect Dis [Internet]. 2014 Dec [date cited]. http://dx.doi.org/10.3201/eid2012.140908

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