Laboratory diagnostics: Aujeszky’s disease (Pseudorabies - PRV)
What laboratory diagnostic methods can I use to diagnose Aujeszky’s disease? Which one should I choose according to the situation? How do I interpret the results?
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The Aujeszky's disease is caused by a virus that can remain latent and causes respiratory, reproductive and nervous problems.
Alternative names: Pseudorabies (PRV)
It is a very important swine disease caused by a herpesvirus. The virus can remain latent in the nervous tissue of the pig for long periods of time, and be reactivated. Once the virus has been introduced in a farm, it normally persists in it and can continuously affect performance at different levels. The virus can survive up to 3 weeks outside the pig. Acute outbreaks of the disease can be produced when a virulent strain affects for the first time a susceptible farm, in which no vaccination against this disease has been practiced. The virus crosses the uterus and placenta and infects piglets. The pig is the main host. It can affect other species that normally do not transmit the disease, including cows, horses, dogs and cats, which can show nervous symptoms and die. There is no information regarding human infection.
Sows
Lactating piglets
Weaners and growers
Other species
Additionally, the presence of other diseases like PRRS, classical swine fever, PCV2 etc. can increase the severity of the disease.
Serology analysis confirm the diagnosis.
What laboratory diagnostic methods can I use to diagnose Aujeszky’s disease? Which one should I choose according to the situation? How do I interpret the results?
A farm in China observed ocular infection in piglets with pseudorabies virus (Aujeszky's disease), a manifestation of the disease not previously reported.