Laboratory diagnostics: Ileitis (Lawsonia intracellularis)
What laboratory diagnostic methods can I use to diagnose ileitis? Which one should I choose according to the situation? How do I interpret the results?
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The disease has three different presentations: porcine intestinal adenopathy (PIA), an abnormal proliferation of the intestinal mucosa; necrotic enteritis (NI), where the proliferated cells of the small intestine die and get detached with a gross thickening of the small intestine (hosepipe gut); and acute hemorrhagic ileitis,an hyper-acute inflammation which causes massive bleeding.
Alternative names: Lawsonia intracellularis, porcine intestinal adenopathy (PIA), necrotic enteritis (NI), hosepipe gut
Describes a group of conditions that imply pathological changes in the small intestine associated to the bacteria Lawsonia intracellularis, which, as its name indicates, lives inside the intestinal cells. The organism is present in all (or almost all) farms. The disease has three different presentations: porcine intestinal adenopathy (PIA), an abnormal proliferation of the intestinal mucosa; necrotic enteritis (NI), where the proliferated cells of the small intestine die and get detached with a gross thickening of the small intestine (hosepipe gut); and acute hemorrhagic ileitis, an hyper-acute inflammation which causes massive bleeding. In the latter there is massive bleeding into the small intestine, hence the name of bloody gut and this is the most common form in growing pigs and gilts.
The organism is impossible to keep out of farms probably because it also infects other species including horses. Infected feces are the major vehicle for spread around the farm.
Gilts
Usually showing the hemorrhagic acute disease:.
Weaners and growers
PIA and NI clinical signs are different form hemorrhagic acute ileitis.
Porcine Intestinal Adenopathy (PIA)
Lactating piglets
Not fully understood.
Based on the clinical picture, post-mortem examinations, histology of the gut wall and demonstrating the presence of the organism in feces by PCR test. A serological ELISA test is also available.
Use antibiotics to treat sick pigs.
Strategic use of antibiotics at high risk times.
A good hygiene and the use of oral or injectable vaccines are recommended.
What laboratory diagnostic methods can I use to diagnose ileitis? Which one should I choose according to the situation? How do I interpret the results?