The effect of the feed additives on the morphological characteristics and proliferation capacity of small intestinal crypt epithelium varied when mitotic indices in groups were compared. In comparison with group C, the enterocytes were higher in group E2 in the jejunum and smaller in the ileum. Administration of the Ki-67 antibody resulted in fewer positive reactions in the jejunum in group E1 than in group C. Enterocyte proliferation in crypt epithelium decreased after the administration of the probiotic or the prebiotic vs. the antibiotic, but the absence of significant differences between the groups may suggest that these feed additives have no adverse effect on the mucosal epithelial cells.
A. Rekiel1, W. Bielecki, J. Więcek, J. Kulisiewicz. Histological Changes in the Small Intestinal Epithelium in Fattening Pigs Fed Selected Feed Additives. Acta Vet. Brno. 2010. Vol. 79: 67-71.