X
XLinkedinWhatsAppTelegramTelegram
0

Intestinal metabolism of weaned piglets fed a typical United States or European diet with or without supplementation of tributyrin and lactitol

The supplementation of slowly released tributyrin and lactitol in piglet diets may overcome the adverse effects of vegetable protein sources during the nursery phase
5 March 2009
X
XLinkedinWhatsAppTelegramTelegram
0
It has been observed that the synergistic effect of a fermentable substrate, lactitol, and a precursor of butyric acid, tributyrin, can improve the trophic status of the intestinal mucosa in the gut of nursery piglets and control intestinal histamine. The objective of the present study was to investigate the effects of supplementation of a microencapsulated blend of tributyrin and lactitol (TL) to a standard EU diet without antibiotic growth promoters on intestinal metabolism and mucosa development of weaned piglets and to compare it with a standard US diet containing animal proteins, zinc oxide, copper sulphate, and carbadox.

Ninety piglets weaned at 21d were distributed into 3 dietary groups consisting of 5 replicates each: 1) US diet supplemented with 55 mg/kg of carbadox, and 2.5% each of plasma proteins and spray-dried blood cells in the first phase, 3,055 mg/kg of Zn in the first and second phases, and 180 mg/kg of Cu in the third phase; 2) EU diet based on vegetable proteins and no antibiotics; and 3) the same EU diet supplemented with 3,000 mg/kg of microencapsulated TL. The study was divided into 3 different phases: 0 to 7, 8 to 21, and 22 to 35 d. On d 7, 21, and 35, animals were weighed, and feed consumption and efficiency were determined. On d 14 and 35, one pig per pen was killed, and the intestinal contents and mucosa from the proximal, middle, distal jejunum and the ileum were sampled. Intestinal wall sections were fixed for histological analysis, and intestinal content was used for volatile fatty acids (VFA), ammonia, and polyamine analysis.

Throughout the study (d 0 to 35), the US diet had greater ADG and ADFI than the EU diet (P < 0.05). The EU diet supplemented with TL tended to have 11% greater ADG (P=0.17). A reduction of 10% in the proximal and middle jejunum villi length (P<0.05) and an increase in crypt size in proximal jejunum (P<0.05) was observed for those animals fed the EU die than those fed the US diet. The TL supplementation resulted in longer villi along the jejunum and less deep crypts in the proximal jejunum (+15.9 and -8.9%, respectively; P<0.05) than the unsupplemented EU diet. The TL diet increased the concentrations of cadaverine and putrescine in the small intestine (P<0.05) and seemed to increase cadaverine, histamine, putrescine, and spermine in the large intestine by 1.5- to 10-fold compared with the US or EU diet. At d 14 of the study, the cecal contents showed no differences in VFA concentrations. At d 35, cecal valeric acid concentration was greater for the EU-based diets compared with the US diet (P<0.05). Cecal acetic and propionic acid proportions were the greatest and the least (P<0.05), respectively, for the US diet. In conclusion, the use of slowly released tributyrin and lactitol seemed to be an effective tool to partially overcome the lack of animal proteins, carbadox, zinc oxide, and copper sulphate in the EU vegetable diets for piglets.

A Piva, E Grilli, L Fabbri, V Pizzamiglio, PP Gatta, F Galvano, M Bognanno, L Fiorentini, J Woli?ski, R Zabielski and JA Patterson. 2008. Journal of Animal Science. 86:2952-2961.

Article Comments

This area is not intended to be a place to consult authors about their articles, but rather a place for open discussion among pig333.com users.
Leave a new Comment

Access restricted to 333 users. In order to post a comment you must be logged in.

You are not subscribed to this list Swine News

Swine industry news in your email

Log in and sign up on the list

Related articles

You are not subscribed to this list Swine News

Swine industry news in your email

Log in and sign up on the list