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Valine supplementation improves immune and endocrine function of lactating sows

Dietary valine supplementation increases serum albumin, IgM, IgG and prolactin concentrations.

14 November 2013
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In previous study, dietary valine supplementation improved sow performance, it may be related to immune and endocrinology function improvement. Thirty-two healthy sows (Landrace x Yorkshire, similar parity, and body condition) were assigned to fed one of the four diets: basal diet (0.93 % Lysine, 0.84 % Valine) or basal diet supplemented with 0.10 %, 0.25 %, and 0.40 % valine respectively from 107 days of gestation to 21 days of lactation. Blood samples were collected at 10 and 18 days of lactation, milk samples were collected at 1 and 10 days of lactation.

The results showed that dietary valine supplementation significantly increased serum albumin concentrations at 10 and 18 days of lactation (P<0.05), and increased serum Immunoglobulin M, Immunoglobulin G and Prolactin concentrations at 18 days (P<0.05) of lactation. Valine supplementation also significantly increased milk insulin concentrations at 14 days of lactation (P<0.05), and increased milk growth hormone concentrations at 1 and 14 days of lactation. Dietary valine supplementation tended to increase milk ALB and IgM concentrations (P>0.05) and tend to reduce diarrhoea rate in suckling pigs (P>0.05).

Therefore, it was suggested that better performance of sows fed valine supplemented diet could be mainly related to improved sows’ immune function and increased milk-borne growth factors concentrations.

Yi, P., Yi, C., Shao-Hui, F., Li-Xiang, C. and Jian-Hua, H. (2013). Dietary valine supplementation improves immune and endocrine function of lactating sows. Amino Acids 45:563–612. 13th International Congress on Amino Acids, Peptides and Proteins, p.575. DOI 10.1007/s00726-013-1540-y

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