Vaccines and PCV2 evolution
Distinct PCV2 variants are circulating in commercial pig farms. How the vaccine induced immunity may affect PCV2 evolution?
Page 4 of articles about pcv2
PCV2 vaccination reduces antibiotic consumption in swine production
The benefit on antibiotic use is particularly clear when herds are multicontaminated by pathogenic virus and bacteria, allowing also to maintain animal welfare and operational productivity, but a good immunity against PCV2 is effective also in high health status herds.
The presence of six potentially pathogenic viruses in pigs suffering from post-weaning multisystemic wasting syndrome
Co-infection with PRRSV enforces clinical signs of PMWS, the influence of other viral co-infections is not clear.
DTH: A new option for checking the compliance of the vaccination against PCV2
It is a test that allows the verification of the carrying out and/or the quality of the vaccination in cases such as the entrance of piglets for their fattening.
Multiple routes of porcine circovirus type 2 transmission to piglets in the presence of maternal immunity
These findings illustrate the importance of maternal infection, despite robust anti-PCV2 immunity, in early infection of newborn piglets.
Effect of PCV2 vaccination on PCV2-viremic piglets after experimental PCV2 challenge
The objective of this study was to evaluate the effect of porcine circovirus type 2 (PCV2) vaccines on PCV2-viremic and -seropositive piglets born from naturally PCV2-infected sows against postnatal PCV2 challenge.
Vaccination failures in the control of PCV disease
The first cause of PCV vaccine failure is the purchase and use of generic vaccine of low quality and titre, but the exact cause of the failures can occur in various forms.
Influence of age on the effectiveness of PCV2 vaccination in piglets with high levels of maternally derived antibodies
The findings of this study have implications for future PCV2 vaccine testing and administration strategies.
Global gene expression profiling of myeloid immune cell subsets in response to in vitro challenge with PCV2b
PCV2b challenge increases the expression of a large number of immune-related and pro-apoptotic genes mainly in MoDC, which possibly explain the increased inflammation.
Clinical case: Reproductive disorders in a newly established herd
The veterinarian is called from a new established herd in Brittany because some clinical signs appear on gilts from the two first deliveries introduced in the farm.
Novel PCV2 variants also known as mutant PCV2: Are current vaccines protective?
During 2012 PCV2 variants or mutants (mPCV2) appeared in the USA and were frequently associated with PCV-associated diseases. The possibility of lack of cross-protection of commercial vaccines against mPCV2 is now of major concern.
Humoral response and colostral antibody transfer following 'one-dose' pre-mating vaccination of sows against porcine circovirus type-2
One-dose vaccination of sows against PCV2 induces colostral antibody transfer.
Modelling PCV2 course of infection in a farrow-to-finish farm
Reducing piglets mingling in farrowing and nursery facilities was found to delay the infectious process leading to a lower number of early infections. Clustering piglets by litter in small units after weaning also decreased significantly the probability of early infection.
Placental transmission of porcine circovirus type 2
In conclusion, placental transmission of PCV-2 from a non-immune sow to fetuses is possible when the infection of the dam occurs before gestation or after 62 days of gestation.
The path to profitability – assessing when the benefit of animal health interventions justifies the cost in wean-to-market
What further increases profitability in pig production is not minimizing costs, but maximizing revenue.
Diagnosis of PCV2-related diseases: a matter of order
Despite the evident usefulness of laboratory diagnosis, we must not forget that a field necropsy allows us to us recover part of the loss caused by the death of the animal.