Mycoplasma hyopneumoniae: Dynamics of Immunity and Physiology
The interaction between M. hyopneumoniae and its host make M. hyopneumoniae one of the most important contributors to porcine respiratory disease.
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The interaction between M. hyopneumoniae and its host make M. hyopneumoniae one of the most important contributors to porcine respiratory disease.
Pathogens that are transmitted mostly through direct, pig to pig, contact are generally contained with today’s biosecurity programs and pig flow strategies. However, pathogens using multiple routes of transmission seem to evade standard biosecurity programs.
Recent reports still show high prevalence of the pathogen in most pig producing countries.
PRRSV by itself may induce mild-to-severe respiratory disease but rarely results in mortality.
Knowledge of the dynamics of infection within the herd will allow implementation of better control strategies in affected herds.
Although a commensal, M. hyorhinis may cause serious systemic disease through mechanisms that are not fully understood.
It has been shown that the efficacy of PCV2 vaccines was dramatically decreased in the context of husbandry deviations such as excess of cross-fostering, mingling at weaning or very large groups in nursery.
The prevalence of pleurisy is surprisingly high among pigs at slaughter. A recent review of available data ranged from 12.5% in the UK, 26% in Spain, to 41% of individual pigs slaughtered in one Norwegian study.
Experimental Mhyo and PCV2 co-inoculations have resulted in somewhat divergent results.
In July 2010 a severe respiratory disease occurred in the farm: coughing in gilts, and coughing and depression in fatteners concomitantly to an increase of the mean stillborn and mummified piglet rate in a batch of sows.
Between 1995 and 1997, at the beginning of an epizootic called “maladie de l’amagrissement du porcelet” (MAP), it was observed that the farms that were most affected and that had the most losses, generally presented obvious deviations from what we would consider to be a suitable management of the animals and facilities. This is why Dr. François Madec made a list of management practices with the aim of improving the anomalous situation observed.