Page 2 of articles about PCV2

A competitive ELISA differentiating PCV2 antibodies from mixture of PCV1/PCV2 antibodies in pig sera

The need for developing PCV2-specific ELISA methods is urgent to evaluate PCV2 antibody level in exclusion of PCV1 antibody interference after PCV2 vaccination.

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Electron micrograph of two inclusion bodies in the cytoplasm of a macrophage, including a very high number of PCV2 particles. 150.000x. Source: Carolina Rodríguez-Cariño, CReSA

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Global molecular genetic analysis of PCV2

The current diagnostic tests are very powerful, allowing us to detect even small changes in the genome of a virus, but what do they tell us?

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Figure 2. Maximum likelihood phylogenetic tree. The 729 ORF2 sequences from the UMN-VDL PCV2 database are colored by year acquired. The genotypes are noted.

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The impact of intensive vaccination on PCV2 epidemiology

The decrease in PCV2a and PCV2b genotypes over time and the increase in PCV2d in 2012 may be due more to other, unknown, factors than to immunological selection resulting from PCV2a-based vaccination.

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HealthAbstract

Detection of a novel circovirus PCV3 in pigs with cardiac and multi-systemic inflammation

In all three cases we characterized the genome of a new circovirus we called PCV3.

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Sketch showing a bronchoalveolar lavage and bronchial scraping

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Sampling for the detection of agents of the porcine respiratory disease complex: Bronchoalveolar lavage or bronchial scraping?

Many veterinarians find bronchial scraping a less invasive and, above all, simpler sampling method than bronchoalveolar lavage.

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PCV3: A novel porcine circovirus associated with PDNS and reproductive failure

Here, a novel porcine circovirus (PCV3) that is distantly related to known circoviruses was identified in sows with porcine dermatitis and nephropathy syndrome (PDNS) and reproductive failure.

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Impact of maternally derived immunity on piglets’ immune response and protection against PCV2 after vaccination at different age

This study was aimed at evaluating the clinical protection, the level of Porcine circovirus type 2 (PCV2) viremia and the immune response (antibodies and IFN-γ secreting cells (SC)) in piglets derived from PCV2 vaccinated sows and themselves vaccinated against PCV2 at different age, namely at 4, 6 and 8 weeks.

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Assessment of different samples to detect main swine respiratory pathogens

The data present bronchial scraping as an equally effective or even better alternative to bronchoalveolar lavage fluid for detecting main porcine respiratory disease complex agents.

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The pie chart represents the percentage of abortions in the first and second stage of pregnancy, respectively. The bar chart represents the seasonality of abortions.

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Infectious agents identified in aborted porcine foetuses

PCV-2 and PRRS are the most common infectious causes of abortions. Most abortions are also found to occur during the colder months, regardless of their cause.

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The impact of 6 years of PCV2 vaccination on viral presence and immunity in pigs across the United States

PCV2 vaccination is nearly universal. Has viral presence decreased after 6 years of vaccination? Could vaccination policies be changed?

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Influence of four commercial PCV2 vaccines on the improvement of production parameters in pigs with maternally derived antibodies

In the presence of high MDA levels, piglets immunized with four commercial PCV2 vaccines showed a significantly reduction of PCV2 infected pigs, viral load...

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Influence of PCV2 vaccination on the level of antimicrobial consumption

The estimated impact of PCV-2 vaccination revealed a highly significant decline in total antimicrobial drug use on finishing farms.

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Health protocols for replacements: respiratory and systemic diseases (2/3)

We are talking about PRRSV, M. hyo, PCV2, App and swine influenza virus.

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National reduction in PCV2 prevalence following introduction of vaccination

Since the introduction of PCV2 vaccines in 2006, viral presence and viral loads have greatly decreased, and a genotypic shift dominated by PCV2b has occurred.

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Comparative efficacy of concurrent administration of a PCV2 vaccine plus a PRRSV in pigs challenged with both viruses

Under the conditions of this study, it makes no difference to protection whether PCV2 and PRRSV vaccines are administered concurrently. Concurrent vaccination is efficacious for controlling co-infection with PCV2 and PRRSV.

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Three months pigs with PCV2-SD. Note the marked spine, indicative of growth retardation, and body pallor

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The challenge of Porcine Circovirus type 2 (PCV2) intra-specific taxonomic classification

All available vaccines in the European and North-American market are based on PCV2a genotype, while the most prevalent ones are PCV2b and PCV2d ones. Although significant level of cross-protection among these three genotypes has been demonstrated, it would be interesting to assess if vaccine efficiency would be equivalent in front of all these different genotypes.